Port Salerno, Florida is a small community located in Martin County Florida. Port Salerno is also located in the heart of the Manatee Pocket region which is frequented by serious sport fisherman from across the world. Boaters absolutely love the ease in which you can reach many fishing destinations from the Manatee Pocket location. Port Salerno is strategically situated where the Atlantic Ocean meets the Indian River allowing for easy access to all of the hot fishing spots in this area of Florida.